Which topical agent is used to treat rosacea?

• A. Azelaic acid
• B. Metrogel (metronidazole) gel
• C. Doxycycline
• D. Benzoyl peroxide

Answer: (B)

Rosacea treatment centers on calming inflammation in the facial skin and choosing therapies that are well tolerated. Topical metronidazole (Metrogel) is a common first-line option because it specifically reduces inflammatory papules and pustules and helps lessen redness, all with a favorable safety profile for sensitive facial skin. Its anti-inflammatory effects help diminish the immune response in rosacea, which is why it often yields noticeable improvement with relatively few local side effects.

Azelaic acid is another topical choice for rosacea and offers antimicrobial and anti-inflammatory benefits, but metronidazole gel is typically preferred when aiming for reliable lesion reduction and tolerability. Doxycycline, while effective, is usually reserved for more moderate to severe disease and is taken systemically, not applied topically. Benzoyl peroxide is primarily used for acne and can irritate rosacea-prone skin, making it less suitable.