Which lab pattern is most consistent with hyperthyroidism?

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Multiple Choice

Which lab pattern is most consistent with hyperthyroidism?

Explanation:
When thyroid hormone levels rise, they feed back on the pituitary to suppress TSH production. In overt hyperthyroidism, T4 and T3 are elevated while TSH is suppressed. So the lab pattern with low TSH and high T4 (and often high T3) fits hyperthyroidism best. Patterns with high TSH and normal T4 point to hypothyroidism or subclinical hypothyroidism, while low TSH with low T4 or normal TSH with high T4 do not match the typical hyperthyroid state.

When thyroid hormone levels rise, they feed back on the pituitary to suppress TSH production. In overt hyperthyroidism, T4 and T3 are elevated while TSH is suppressed. So the lab pattern with low TSH and high T4 (and often high T3) fits hyperthyroidism best. Patterns with high TSH and normal T4 point to hypothyroidism or subclinical hypothyroidism, while low TSH with low T4 or normal TSH with high T4 do not match the typical hyperthyroid state.

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