Cutaneous anthrax treatment typically includes which regimen?

• A. Doxycycline bid, ciprofloxacin bid, or levofloxacin bid for 7-10 days; 60 days if bioterrorism suspected
• B. Amoxicillin
• C. Clindamycin
• D. Erythromycin

Answer: (A)

The main idea is using antibiotics with proven activity against Bacillus anthracis that penetrate skin lesions and stop spread. For cutaneous anthrax, an oral antibiotic such as doxycycline or a fluoroquinolone (ciprofloxacin or levofloxacin) is given twice daily for about 7–10 days. If there’s a concern for bioterrorism exposure or inhalational risk, prophylaxis is extended to 60 days to cover the incubation period and potential latent infection. These agents are preferred because of reliable efficacy and good tissue penetration in skin disease. Other antibiotics like amoxicillin, clindamycin, or erythromycin aren’t considered first-line due to less consistent efficacy in this context.